
Pathology Outlines - Neutrophil maturation
Sep 1, 2012 · Progresses from myeloid stem cell to myeloblast to promyelocyte to neutrophilic myelocyte to neutrophilic metamyelocyte to neutrophilic band to segmented neutrophil …
Pathology Outlines - AML without maturation (FAB AML M1)
Feb 1, 2013 · Microscopic (histologic) description Typically markedly hypercellular marrow, but normocellular and hypocellular cases occur Very immature cells, usually round with few azurophilic …
Pathology Outlines - Acute myelomonocytic leukemia (AMML)
Mar 21, 2023 · As per the upcoming 2022 5th edition of WHO classification, acute myelomonocytic leukemia (AMML) is a distinct entity within acute myeloid leukemia, defined by differentiation category
Pathology Outlines - Basophils
Aug 1, 2012 · Microscopic (histologic) description Basophilic granules are metachromatic (reddish purple) with Toluidine blue and Alcian blue; are also water soluble Basophilic myeloblast: difficult to …
Pathology Outlines - Eosinophils
Aug 1, 2012 · Eosinophilic promyelocyte: intermediate in development between a myeloblast and myelocyte; 15 microns in diameter with large nucleus and nucleolus; contains a few undifferentiated …
Pathology Outlines - Monocytes
Sep 1, 2012 · Monocytes usually < 1% of bone marrow cells Develop from myeloid stem cell, to monoblast to promonocyte to monocyte (bone marrow) to monocyte (peripheral blood) to …
Pathology Outlines - MDS with single lineage dysplasia
Dec 9, 2021 · Myelodysplastic syndrome with single lineage dysplasia (MDS SLD) is defined as persistent unexplained cytopenias (anemia [most common], neutropenia or thrombocytopenia) or …
Transient abnormal myelopoiesis associated with Down syndrome
May 20, 2021 · Transient abnormal myelopoiesis associated with Down syndrome is a transient disorder of newborns with Down syndrome or phenotypically normal neonates with trisomy 21 mosaicism.
Pathology Outlines - Megaloblastic anemia
Oct 11, 2021 · Megaloblastic anemia is a disorder of impaired DNA synthesis (with normal RNA synthesis) that manifests with the presence of megaloblasts in the bone marrow resulting in …
Pathology Outlines - AML with maturation (FAB AML M2)
Sep 29, 2025 · Acute myeloid leukemia (AML) with granulocytic maturation but lacking defining genetic aberrations