Type 1 diabetes confers a cardiovascular burden that is often obscured by the young age of affected individuals and by the longstanding focus on microvascular rather than macrovascular complications.

Clinical trial datasets are becoming increasingly complex, yet the format of their dissemination remains largely static.1 ...

Urinary stone disease is common, associated with substantial morbidity, has a high recurrence rate, and affects quality of life.1,2 Consumption of large volumes of fluids is a foundational strategy ...

Among today's most pressing development challenges is the matching of financing to health needs. One of the critically underfunded global priorities is adolescent health, with adolescents (aged 10–24 ...

The 2021 Lancet Commission on diagnostics reported that nearly half of the world's population has limited access to basic diagnostic services.1 Less than 5% of diagnostics and less than 1% of vaccines ...

Although malaria elimination has been reported in 14 countries, human health risk reduction against vector-borne diseases remains dire. With neither effective treatment nor widely available ...

Between Nov 24 and Nov 27, 2025, the International Chair in Bioethics held its 17th World Conference on Bioethics, Medical Ethics, and Health Law in Ljubljana, Slovenia.1 Despite being hosted in a ...

We read with interest the results of the HARMONi-6 trial by Zhiwei Chen and colleagues,1 which showed that ivonescimab plus chemotherapy improved progression-free survival versus tislelizumab plus ...

Respiratory medicine is deeply connected to social and structural determinants of health in terms of the diseases that we try to prevent and we treat. I think that connection to people's lives and ...

The DIRECT ANGIO randomised clinical trial by Benjamin Gory and colleagues1 in The Lancet Neurology was designed to test a biologically compelling premise: that a direct transfer to angiography suite ...

As the inaugural Director of the new Parkinson's Research Centre, funded by the UK Dementia Research Institute and Parkinson's UK, Professor Miratul Muqit (University of Dundee, UK) hopes to untangle ...

Neuropathological confirmation of Alzheimer's disease is defined by the presence of extracellular amyloid-β plaques and intracellular neurofibrillary tau tangles. A central challenge to the ...