Key points Canada’s health systems are stressed with increasing demands for health care and services. The causes of this stress are multifactorial and include an aging population and a health ...

Background: Subclinical hypothyroidism has been linked to adverse renal outcomes, but it is unknown whether treatment of subclinical hypothyroidism reduces the risk of these adverse outcomes. We ...

Key points The provision of health care is hard and, understandably, clinicians struggle. Beyond meaningful health care interactions, clinicians must also integrate large volumes of demographic, ...

Care should include explicit statements affirming patient choice. Clinicians with faith-based objections should provide timely, tolerant referral; judgmental or obstructive care may result in ...

KEY POINTS Recent changes to Canadian legislation effectively created 2 pathways for medical assistance in dying (MAiD), where death is or is not reasonably foreseeable, with implications for frail ...

HIV-1 can be successfully treated with long-acting injectable antiretroviral therapy A dual regimen combining the integrase strand transfer inhibitor cabotegravir with the nonnucleoside reverse ...

Figure 1: (A) Peripheral blood smear showing erythrocytes with basophilic stippling (arrows) in a 47-year-old male plumber with lead poisoning. (B) Burton line (arrows) in some of the patient’s gum ...

Figure 1: (A) Numerous black–brown granules attached to the left eyelashes and eyelids of a 77-year-old woman with phthiriasis palpebrarum. (B) Dermoscopy showed multiple lice and ovoid nits on the ...

Primary ovarian insufficiency (POI) affects 1% of reproductive-aged women In POI, ovarian follicles become depleted or dysfunctional in people younger than 40 years. Risk factors include family ...

Obstructive sleep apnea in children peaks around age 4–6 years Obstructive sleep apnea (OSA) is characterized by partial or complete airway obstruction during sleep. Prevalence is about 1.2%. 1 ...

KEY POINTS Clinicians may be concerned about the potential of electronic patient portals to disrupt the therapeutic relationship, deliver medicolegal burdens or harm patients, but these fears are ...

Figure 1: (A) Abdominal contrast-enhanced computed tomography scan of a 54-year-old man with phlegmonous gastritis showing diffuse circumferential thickening of the gastric wall. (B) Upper ...