Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Facilities operated by the US Department of Energy (DOE) are required to have extensive worker safety and health programs by regulation. We describe how Argonne National Laboratory (ANL) has ...

File Submission Submit your own Manuscript PDF File—and provide your native LaTeX manuscript package as a ZIP archive. Compress the following into a single ZIP archive (.zip) file: Main body of the ...

The electrocatalytic nitrogen reduction reaction (ENRR) offers a sustainable and promising approach for synthesizing ammonia under ambient conditions, providing an alternative to conventional ...

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Silver nanoparticles (AgNPs) are widely recognized for their unique optical, electronic, and antibacterial properties, enabling their use in biosensing, photonics, electronics, drug delivery, and ...

Plug flow has a huge chemical potential of charge separation at the solid−liquid interface not limited by the Debye length for effectively generating electricity via harvesting energy from rain.

RNA therapeutics offer a promising approach to cancer treatment by precisely regulating cancer-related genes. While lipid nanoparticles (LNPs) are currently the most advanced nonviral clinically ...

We report an asymmetric total synthesis of (−)-illisimonin A, a sesquiterpene natural product with neurotrophic activity. Illisimonin A possesses a unique cage-like 5/5/5/5/5 pentacyclic scaffold ...

Solid-state batteries (SSBs) with silicon anodes could enable improved safety and energy density compared to lithium-ion batteries. However, degradation arising from the massive volumetric changes of ...

Fluorescence emitters with a multiple-resonant (MR) effect have become a research hotspot. These MR emitters mainly consist of polycyclic aromatic hydrocarbons with boron/nitrogen, nitrogen/carbonyl, ...