While the findings align with previous research linking smoking to ALS, researchers found no consistent evidence that heavier or longer smoking exposure further increased that ris ...

RAG-17 is an experimental RNA-targeting therapy designed to lower toxic SOD1 protein in people with SOD1-ALS. A six-person trial found RAG-17 was well tolerated, with no serious side effects. RAG-17 ...

Although I continue to rely on a rollator to help me walk inside the house and a mobility scooter when I’m out and about, getting the power wheelchair was a strategic, planning-ahead decision. I live ...

Study examines Qalsody safety after approval “This study is the first to systematically conduct a post-marketing [safety] ...

Preventing TDP-43 from forming toxic clumps is widely seen as a promising strategy for developing new ALS treatments. But it’s been difficult for scientists to find a way to prevent these clumps ...

Over the last five years, Canadian ALS clinics have shifted from offering genetic testing mainly to people with a family ...

A PBS documentary, "Loving John," explores a gay American Samoan man's final years with ALS. It highlights the disease's ...

A self-balancing robotic exoskeleton was found safe and feasible for ALS patients with gait impairment. It helps patients practice walking hands-free, improving mobility, posture, and well-being.

Australian data links over 10% of ALS cases to known genetic mutations. The SALSA-SGC consortium collects data to understand ALS causes and progression. The project brings together seven major motor ...

An expanded access program for Qalsody in ALS patients was feasible and well-tolerated. The program provided Qalsody to 11 ALS patients ineligible for trials. A mixed funding model, including ...

I walked with our dog, Comet, on a trail in the woods behind our house. The woods felt cool out of the hot sun. Light filtered through the trees overhead as I breathed in the rich smell of summer ...