Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left ...

Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However, in some cases, chromosomes do not fully separate, leaving behind thin strands of DNA known as ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...

A protein best known for protecting the ends of chromosomes also helps muscle stem cells preserve their identity and repair ...

A baby can inherit one healthy copy of TBX5 and still develop serious heart defects if the other copy does not work. That genetic imbalance is one cause of congenital heart disease, the most common ...

Specialized cells in the human body make biological trade-offs to perform certain jobs. To support the large, hardworking hearts that power other organs, heart cells have evolved to be extremely ...

Aging muscles may not lose the signals needed for repair. Instead, those signals may remain in place but become chemically ...