In this study, researchers aimed to determine whether BCMA-directed CAR T-cell therapy is a feasible first-line option for newly diagnosed multiple myeloma patients who are ineligible for ASCT.

Although the primary endpoint was not met, axitinib was associated with significantly increased PFS and ORR for patients with previously-treated, advanced extrapancreatic neuroendocrine tumors.

Female breast cancer incidence is stable and mortality is declining in high-income countries, while it is increasing in low-income countries, according to research published online March 2 in The ...

Daily aspirin use does not offer a reliable way to prevent colorectal cancer (CRC), according to a review published online Feb 26 in the Cochrane Database of Systematic Reviews. Zhaolun Cai, MD, from ...

Investigators sought to determine the effect of “Smart PSA” guidelines on screening behavior and biopsy outcomes among Black men.

The combination of tislelizumab and chemotherapy produced sustained and clinically meaningful survival benefits with manageable toxicity among patients ...

In prostate cancer, prostate brachytherapy boost improves biochemical failure at 10 years but does not prolong long-term OS ...

In this study, researchers aimed to determine whether overall survival is superior with first-line CDK4/6i use compared to second-line use in HR-positive, HER-negative advanced breast cancer.

Adding LAG-3 or TIGIT ICIs to enfortumab vedotin + pembrolizumab did not improve efficacy in pts with locally advanced or ...

Capivasertib+abiraterone was associated with more symptomatic AEs but did not impact HRQoL in patients with PTEN-deficient ...

In the phase 3 VERIFY trial, rusfertide was associated with a significantly higher proportion of patients achieving clinical response compared with placebo.

In this analysis, study researchers aimed to assess the association between county-level proximity to nuclear power plants and cancer mortality.