AbstractIntroduction:. Ikaros family zinc finger protein 1 and 3 (IKZF1/3) are essential transcription factors (TF) for the differentiation of B and T lymphocytes. IMiDs (e.g. pomalidomide, CC-220, CC ...
Abstract. The CD47-SIRPα axis functions as an immune checkpoint, transmitting a “don’t eat me” signal to prevent macrophage-mediated phagocytosis of tumor cells. While CD47 is expressed on most immune ...
AbstractFirst-line multiple myeloma treatment has evolved from melphalan–prednisone to quadruplet regimens incorporating proteasome inhibitors, immunomodulatory drugs, anti-CD38 monoclonal antibodies, ...
2Department of Gastroenterological Surgery, International University of Health and Welfare Atami Hospital, Shizuoka, Japan.
Cancer Discov (2026) 16 (3): OF1.
To help defray the rising costs of initial manuscript screening and publication, the AACR journals levy fees as detailed herein. Authors are required to confirm at the time of submission that they ...
Cancer Discov (2026) 16 (3): OF1.
Authors may opt to publish their research under an open access license in any of the AACR hybrid journals. The hybrid AACR journals include: Blood Cancer Discovery; Cancer Discovery; Cancer ...
1 Surgical Pathology Laboratory of the College of Physicians and Surgeons, Columbia University, and the Department of Surgery, the Presbyterian Hospital, New York City Search for other works by this ...
Summary:. Centonze and colleagues demonstrate that KRASG12D inhibition in metastatic colorectal cancer triggers rapid transcriptional reprogramming from a metastasis-associated EMP1+ state to a ...
Cancer Res (2023) 83 (8_Supplement): LB321. Citation Format: Elizabeth Donohue Vo, Yang W. Zhang, Dave Rominger, Jillian M. Silva, Yang J. Zhang, Greg Lee, John ...
1Department of Oncology, University of Lausanne, Lausanne, Switzerland.
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