The NFL Week 2 schedule is headlined by a Super Bowl rematch between the Philadelphia Eagles and Kansas City Chiefs on Sept. 14. Eagles-Chiefs is the FOX late-afternoon national game on Sunday, the lone 3:25 p.m. CT game.

Oh, the injury bug, a dreaded foe for even the most experienced fantasy football managers. We're only a week into the 2025 NFL season and injuries are already impacting lineup decisions across the fantasy world.

The Fanatics Sportsbook promo code will unlock access to FanCash and other strong signup offers for college football and NFL Week 2 games.

With Brock Purdy sidelined by a turf toe injury, Kyle Shanahan will need to be at his best with his play-calling as Mac Jones takes over under center against the Saints.

Caleb Williams and the Chicago Bears got off to a fast start in Week 1 of the 2025 NFL season, but it didn’t stay that way, as they ended up blowing a double-di

Ricky Pearsall is in line to be the 49ers' top wideout for Week 2 while Drake Maye is poised for a bounce-back performance versus Miami.

There is a change at No. 1 and two new members of the top 10 in Nick Shook's QB Index rankings entering Week 2 of the 2025 NFL season. Check out the updated pecking order, 1-32.

Week 2 is headlined by a Super Bowl rematch between the Philadelphia Eagles and Kansas City Chiefs, while across the league several contenders are fighting to avoid the dreaded 0-2 start.