Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes.

Kidney disease has long been considered a progressive and irreversible condition, where treatment focuses only on slowing decline rather than restoring lost function. However, a promising scientific ...

One organ that does the most amount of work, without much fuss or chaos — it’s the kidneys. The “silent multitaskers” of the body perform vital, behind-the-scenes work: filtering waste, balancing ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes.

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding mitochondrial integrity through the combined actions of Parkin–PINK1 and OMA1. The ...

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions. But one of their most life-threatening ...