Researchers argue that, in some situations where machine-learning models are used to allocate scarce resources or opportunities, randomizing decisions in a structured way may lead to fairer outcomes.

A review of all therapeutics receiving a breakthrough designation and approved from 2012 to 2017 found a lack of randomization, double-blinding and control groups in pivotal trials supporting approval ...

The genetic and clinical heterogeneity of breast cancer makes the identification of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively randomized trial to screen ...

Outcome-adaptive randomization is one of the possible elements of an adaptive trial design in which the ratio of patients randomly assigned to the experimental treatment arm versus the control ...

A research team analyzed linguistic approaches to help cancer patients better comprehend the concept of randomization, being assigned by chance to treatment or control groups, in clinical trials.