Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able ...

Torino is a computational workflow that uses biobank-scale RNA-seq data to decode transcript structures and expression levels from read coverage alone.

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Immunotherapy with immune checkpoint inhibitors is standard first-line treatment for advanced renal cell carcinoma (RCC), but ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first ...

The company says the system can benefit pharmaceutical and biotech firms seeking rapid feedback on drug candidates or genome editing.

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes ...