Methods to improve plasmid-mediated transgene expression are needed for gene medicine and gene vaccination applications. To maintain a low risk of insertional mutagenesis-mediated gene activation, ...

Microbiome engineering is at the forefront of improving human health and agricultural productivity. It aims to enhance ecosystem function by altering microbe composition. This can be accomplished ...

CHICAGO, October 08, 2025--(BUSINESS WIRE)--VectorBuilder, a global leader in gene delivery technologies and CDMO services, today announced the publication of the miniVec plasmid system, engineered ...

A research group has constructed versatile genetic tools for Saccharolobus islandicus REY15A, one of the very few archaeal models for archaea biology and CRISPR biology research. Such tools include ...

Plasmid DNA lies at the heart of viral and mRNA vector production because it provides the coding sequences for gene-based advanced therapy medicinal products (ATMPs). Its manufacture is therefore ...

Researchers have developed PlasmidMaker, a versatile automated platform for plasmid design & construction. These circular DNA molecules are used by scientists to introduce new genes into a target ...

The term “plasmid” was coined by Joshua Lederberg in 1952 to describe extrachromosomal genetic elements observed during studies of bacterial conjugation and antibiotic resistance. Their transformation ...

DNA vaccines, wherein a new antigen is inserted into a validated vector, have tremendous potential for deployment in pandemic applications as they can be rapidly produced in a validated, ...

Plasmid DNA is an essential part of cell and gene therapy products. It is utilized as a template vector for cell therapy and non-viral gene therapy and as a raw material to produce adeno-associated ...