Neutralization assays constitute the definitive means to quantify the functional capacity of antibodies to inhibit SARS-CoV-2 entry into host cells. By assessing how serum or monoclonal antibodies ...

The alternative text for this image may have been generated using AI. Fig. 3: Estimated PE by PT 80 to the autologous acquired virus in AMP trials and in NHP studies. The alternative text for this ...

Multiple sublineages of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have dominated the coronavirus disease 2019 pandemic since December 2021. BA.5 is currently ...

Biomedical research faces a ubiquitous and fundamental challenge: Because the goal of the research is to improve human health, the human body is logically the best place to perform experiments.

Mutations of virus and illnesses caused by new variants are still to be expected even in a SARS-CoV-2 situation that has now become endemic. Although the population has developed specific immune ...

In a recent study posted to bioRxiv*, researchers evaluated how angiotensin-converting enzyme 2 (ACE2) expression in target cells impacts neutralization. Study: Receptor binding domain (RBD) ...

These data further support the cross-neutralization ability of the omicron-containing bivalent booster vaccine against emerging omicron subvariants that are not contained in the vaccine. Real-world ...

The COVID-19 pandemic renewed interest in vaccinations, and scientific advancements abound. Developers are continually working to create vaccines that elicit targeted, strong, and long-lasting immune ...

The US Food and Drug Administration (FDA) on Wednesday finalized guidance to help industry develop and validate immune assays for the assessment of the immunogenicity of therapeutic protein products ...