In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew.

Scientists identified a protein that may help Parkinson's disease spread through the brain, opening a potential path to new ...

Parkinson's disease is characterized by the progressive loss of dopaminergic neurons in a specific brain region known as the substantia nigra. This neuronal degeneration is closely linked to ...

The innate immune protein C1q seems to have a thing for neurons. Already implicated in synaptic pruning by microglia, now it is reported to also slow down protein production in neurons of the aging ...

Post-traumatic stress disorder (PTSD) and anxiety disorders are often characterized by fearful responses in specific situations that the mind learns to view as threatening. These fearful responses ...

As you read this sentence, an army of cells patrols your brain. These soldiers slip around neurons, using their gangly appendages to search for threats. If one of them detects a pathogen or injury, it ...

A team at Texas A&M University has shown that tiny biological particles, sprayed into the noses of aged mice, can quiet the ...