A multi-ancestry polygenic risk score improved HCM risk prediction in a diverse U.S. population of more than 258,000 people.

Each year, roughly the same numbers of boys and girls are born. But in individual families, some couples have four or more daughters and no sons, and some have all male children and no female children ...

Modern HIV medicine is based on a common genetic mutation. Now, researchers have traced where and when the mutation arose—and how it protected our ancestors from ancient diseases. What do a ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Researchers have taken an important step toward solving one of the biggest challenges in gene therapy for children with ...

Mutation rates govern the introduction of genetic variation and influence evolutionary trajectories, disease susceptibility and species diversity. Rates are shaped by a balance between DNA damage, ...

Allowing females to mate with multiple males, rather than just one, could help make species more resistant to extinction, ...

Researchers have detected a human genetic variant that influences the sex ratio of children. Additionally, they found that many hidden genetic variants of sex ratio may exist in human populations.