Immune checkpoint inhibitors (ICIs) have reshaped colorectal cancer (CRC) care, but their impact has been most transformative in the biologically distinct subgroup of mismatch repair-deficient (dMMR) ...

Tumor deposits are a significant prognostic factor in colorectal cancer, yet underutilized in N-staging. Ten novel models incorporating tumor deposits showed improved prognostic performance over the ...

Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are packed with immune-suppressing regulatory T cells. New research finally ...

See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Researchers have unveiled a breakthrough showing that a subset of ...

A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how the disease progresses and patient outcomes. These "tissue-resident" microbes ...

The researchers have developed a novel deep learning framework that integrates high-resolution pathology images with spatial transcriptomics and proteomics to reveal the complex intra-tumor ...

A major randomized trial challenges the assumed benefit of tumor debulking in advanced colorectal cancer, showing no survival gain despite increased risks and raising questions about its role in ...

Researchers identified a six-gene signature in microscopic colorectal cancer (CRC) liver metastases that may help predict ...

Researchers have unveiled a breakthrough showing that a subset of colorectal tumors can be eliminated using immunotherapy alone, without chemotherapy or surgery. The finding signals a potential shift ...