Researchers have found that the DNA spools inside human cells are far less tightly wound than textbooks have long suggested.

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...

Researchers at Baylor College of Medicine and collaborating institutions are challenging the traditional understanding of how cancer drugs called histone deacetylase (HDAC) inhibitors function.

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Cell function is determined by how DNA is expressed into proteins. That process includes two main steps—transcription, when ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

Researchers have shown that mice carrying extra copies of the Grik4 gene developed clear signs of anxiety and social ...

The research, published May 27 in Nature, reveals conserved signatures of aging and health decline and introduces new ...

Northwestern Medicine scientists have discovered that little-studied DNA structures play a central role in organizing the human genome and controlling gene activity, according to a new study published ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...