Scientists have discovered a way to control mutation rates in bacteria, paving the way for new strategies to combat antibiotic resistance. Antibiotics are given to kill bad bacteria; however, with ...

A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas fluorescens, providing unprecedented insight into the relationship between gene ...

Mutation dynamics in bacterial populations underpin the generation of genetic diversity that drives adaptation, speciation and the emergence of antimicrobial resistance. Spontaneous base substitutions ...

Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic ...

Another last-resort antibiotic has fallen victim to the rapid evolution of drug-resistant superbugs. The powerful antibiotic combination ceftazidime-avibactam (CZA), widely used to treat severe ...

Certain bacteriophages found in the human gut have mutation hotspots scattered throughout their genomes that help them modify key defense genes, researchers report. Every 15 minutes, someone in the ...

Do bacteria mutate randomly, or do they mutate for a purpose? Researchers have been puzzling over this conundrum for over a century. In 1943, microbiologist Salvador Luria and physicist turned ...

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive ...

These factors include genetic and age-related blood mutations, smoking and infection by oral bacteria. Published in Cancer Discovery, the findings provide new insight into the earliest biological ...

Traditional biochemical methods of studying human gene mutations are often laborious and costly. Now bioengineers at the University of California San Diego have developed a new simple approach to ...